Antiplasmodial and antibacterial agent(s) from Vernonia angulifolia DC
نویسندگان
چکیده
منابع مشابه
Antiplasmodial, Cytotoxic and Acute Toxicity Activities of Vernonia lasiopus
Background: Malaria continues to cause heavy morbidity and mortality and it is the fifth leading cause of death globally. The disease causes over one million deaths annually and affects many more, particularly due to increasing multi-drug resistant strains of Plasmodium falciparum. Sustained investigations in both curative and prophylactic interventions have supported the ethno-pharmacological ...
متن کاملPhytochemical screening and antibacterial activities of Vernonia ambigua, Vernonia blumeoides and Vernonia oocephala (Asteraceae).
Some Vernonia species (Vernonia ambigua, Vernonia blumeoides and Vernonia oocephala) used in Northern Nigerian traditional medicine, were subjected to phytochemical screening using standard procedures. The antibacterial activity using the disc diffusion method as outlined by the NCCLS was carried out on Klebsiella pneumoniae, Streptococcus pyogenes, Staphylococcus aureus, Corynbacterium ulceran...
متن کاملAntiplasmodial hirsutinolides from Vernonia staehelinoides and their utilization towards a simplified pharmacophore.
The dichloromethane extract of the leaves of Vernonia staehelinoides Harv. (Asteraceae) showed in vitro activity (IC(50) approximately 3 microg/ml) against the chloroquine-sensitive (D10) and the chloroquine-resistant (K1) strains of Plasmodium falciparum. Through conventional chromatographic techniques and bioassay-guided fractionation two structurally-related hirsutinolides displaying in vitr...
متن کاملAntiplasmodial, antioxidant and immunomodulatory activities of ethanol extract of Vernonia amygdalina del. Leaf in Swiss mice
Objective: Vernonia amygdalina (V. amygdalina) leaf is locally employed in the Southern region of Nigeria in the treatment of malari a infection. This study evaluated the in vivo antiplasmodial, antioxidant and immunomodulatory effect of ethanol extract of V. amygdalina leaf. Materials and Methods: The active principles of the dried leaf were extracted with ethanol. For quality validation, ch...
متن کاملAntiplasmodial, antioxidant and immunomodulatory activities of ethanol extract of Vernonia amygdalina del. Leaf in Swiss mice
OBJECTIVE Vernonia amygdalina (V. amygdalina) leaf is locally employed in the Southern region of Nigeria in the treatment of malaria infection. This study evaluated the in vivo antiplasmodial, antioxidant and immunomodulatory effect of ethanol extract of V. amygdalina leaf. MATERIALS AND METHODS The active principles of the dried leaf were extracted with ethanol. For quality validation, chemi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: South African Journal of Botany
سال: 2007
ISSN: 0254-6299
DOI: 10.1016/j.sajb.2007.02.029